Single breath-hold Vd(m) calculation as good as multi breath-hold technique in Equilibrium Contrast CMR

Results 54 subjects (median age 49, range 24-81, 26 males) were recruited. We noted poor agreement and correlation in the pre contrast T1s in both blood and myocardium. There was strong correlation, but poor agreement in post contrast T1 measurements. However, mean Vd(m) at equilibrium was 0.258±0.032 using MFA FLASH and 0.263±0.034 with ShMOLLI, with good agreement on Bland Altman analysis (Fig 1), suggesting that the Vd (m) calculation can compensate for the variability in pre contrast T1 measurements. There was also good agreement between the Vd(m) at equilibrium and at potential pseudoequilibrium (Fig 2).